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Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4669757

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

About this item

Full title

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2015-01, Vol.6 (1), p.e1589-e1589

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Primary ovarian insufficiency (POI) is a common cause of infertility in around 1–2% of women aged <40 years. However, the mechanisms that cause POI are still poorly understood. Here we showed that germ cell-specific knockout of an essential autophagy induction gene
Atg7
led to subfertility in female mice. The subfertility of
Atg7
deleti...

Alternative Titles

Full title

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4669757

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4669757

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/cddis.2014.559

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