Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Primary ovarian insufficiency (POI) is a common cause of infertility in around 1–2% of women aged <40 years. However, the mechanisms that cause POI are still poorly understood. Here we showed that germ cell-specific knockout of an essential autophagy induction gene
Atg7
led to subfertility in female mice. The subfertility of
Atg7
deleti...
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Full title
Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4669757
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4669757
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2014.559