Mycobacterium
spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by
Mycobacterium
spp.With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus
Mycobacterium
. This platform currently provides information of 2108 genome sequences of at least 55
Mycobacterium
spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the
Mycobacterium
strains and the SuperClassification tool for the phylogenic classification of the
Mycobacterium
strains and a specialized classification system for strains of
Mycobacterium abscessus
. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL:
http://mycobacterium.um.edu
.my...

MycoCAP - Mycobacterium Comparative Analysis Platform

10.1038/srep18227