Immune activation caused by vascular oxidation promotes fibrosis and hypertension
Immune activation caused by vascular oxidation promotes fibrosis and hypertension
About this item
Full title
Author / Creator
Wu, Jing , Saleh, Mohamed A , Kirabo, Annet , Itani, Hana A , Montaniel, Kim Ramil C , Xiao, Liang , Chen, Wei , Mernaugh, Raymond L , Cai, Hua , Bernstein, Kenneth E , Goronzy, Jörg J , Weyand, Cornelia M , Curci, John A , Barbaro, Natalia R , Moreno, Heitor , Davies, Sean S , Roberts, 2nd, L Jackson , Madhur, Meena S and Harrison, David G
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Vascular oxidative injury accompanies many common conditions associated with hypertension. In the present study, we employed mouse models with excessive vascular production of ROS (tg(sm/p22phox) mice, which overexpress the NADPH oxidase subunit p22(phox) in smooth muscle, and mice with vascular-specific deletion of extracellular SOD) and have show...
Alternative Titles
Full title
Immune activation caused by vascular oxidation promotes fibrosis and hypertension
Authors, Artists and Contributors
Author / Creator
Saleh, Mohamed A
Kirabo, Annet
Itani, Hana A
Montaniel, Kim Ramil C
Xiao, Liang
Chen, Wei
Mernaugh, Raymond L
Cai, Hua
Bernstein, Kenneth E
Goronzy, Jörg J
Weyand, Cornelia M
Curci, John A
Barbaro, Natalia R
Moreno, Heitor
Davies, Sean S
Roberts, 2nd, L Jackson
Madhur, Meena S
Harrison, David G
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4701546
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4701546
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI80761
