Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cyclotides are diverse plant backbone cyclized peptides that have attracted interest as pharmaceutical scaffolds, but fundamentals of their biosynthetic origin remain elusive. Backbone cyclization is a key enzyme-mediated step of cyclotide biosynthesis and confers a measure of stability on the resultant cyclotide. Furthermore, cyclization would be...
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Full title
Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703859
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703859
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10199
