Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydr...
Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry
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Publisher
Boston: Springer US
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Language
English
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Boston: Springer US
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Contents
G protein-coupled receptors (GPCRs) have important roles in physiology and pathology, and 40% of drugs currently on the market target GPCRs for the treatment of various diseases. Because of their therapeutic importance, the structural mechanism of GPCR signaling is of great interest in the field of drug discovery. Hydrogen/deuterium exchange mass s...
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Full title
Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4727453
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4727453
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ISSN
1044-0305
E-ISSN
1879-1123
DOI
10.1007/s13361-015-1083-4
