A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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United States: American Association for the Advancement of Science
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Contents
Fusion of intracellular transport vesicles requires soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs) and Sec1/Munc18-family (SM) proteins. Membrane-bridging SNARE complexes are critical for fusion, but their spontaneous assembly is inefficient and may require SM proteins in vivo. We report x-ray structures of Vps33, t...
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Full title
A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4727825
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4727825
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aac7906
