Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
About this item
Full title
Author / Creator
Heyn, Holger , Vidal, Enrique , Ferreira, Humberto J , Vizoso, Miguel , Sayols, Sergi , Gomez, Antonio , Moran, Sebastian , Boque-Sastre, Raquel , Guil, Sonia , Martinez-Cardus, Anna , Lin, Charles Y , Royo, Romina , Sanchez-Mut, Jose V , Martinez, Ramon , Gut, Marta , Torrents, David , Orozco, Modesto , Gut, Ivo , Young, Richard A and Esteller, Manel
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
One of the hallmarks of cancer is the disruption of gene expression patterns. Many molecular lesions contribute to this phenotype, and the importance of aberrant DNA methylation profiles is increasingly recognized. Much of the research effort in this area has examined proximal promoter regions and epigenetic alterations at other loci are not well c...
Alternative Titles
Full title
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Authors, Artists and Contributors
Author / Creator
Vidal, Enrique
Ferreira, Humberto J
Vizoso, Miguel
Sayols, Sergi
Gomez, Antonio
Moran, Sebastian
Boque-Sastre, Raquel
Guil, Sonia
Martinez-Cardus, Anna
Lin, Charles Y
Royo, Romina
Sanchez-Mut, Jose V
Martinez, Ramon
Gut, Marta
Torrents, David
Orozco, Modesto
Gut, Ivo
Young, Richard A
Esteller, Manel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4728783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4728783
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-016-0879-2
