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Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4740743

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

About this item

Full title

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-02, Vol.6 (1), p.20254-20254, Article 20254

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed
in vitro
to exosomes were evaluated. CD4
+
Tconv, CD8
+
T or CD4
+
CD39
+
Treg were isolated from normal donors’ peripheral blood and co-incubated with TEX or exosomes isolated...

Alternative Titles

Full title

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4740743

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4740743

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep20254

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