Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
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The Pharmacogenomics of Bipolar Disorder Study , Pharmacogenomics of Bipolar Disorder Study , Mertens, Jerome , Wang, Qiu-Wen , Kim, Yongsung , Yu, Diana X. , Pham, Son , Yang, Bo , Zheng, Yi , Diffenderfer, Kenneth E. , Zhang, Jian , Soltani, Sheila , Eames, Tameji , Schafer, Simon T. , Boyer, Leah , Marchetto, Maria C. , Nurnberger, John I. , Calabrese, Joseph R. , Oedegaard, Ketil J. , McCarthy, Michael J. , Zandi, Peter P. , Alda, Martin , Nievergelt, Caroline M. , Mi, Shuangli , Brennand, Kristen J. , Kelsoe, John R. , Gage, Fred H. and Yao, Jun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
A neuronal model of bipolar disorder based on induced pluripotent stem cell (iPSC) technology finds hyperactive action-potential firing and differential responsiveness to lithium in iPSC-derived neurons from patients with bipolar disorder.
Efficacy of lithium in bipolar disorder
Lithium is widely used as a mood stabilizer in bipolar disorder,...
Alternative Titles
Full title
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Authors, Artists and Contributors
Author / Creator
Pharmacogenomics of Bipolar Disorder Study
Mertens, Jerome
Wang, Qiu-Wen
Kim, Yongsung
Yu, Diana X.
Pham, Son
Yang, Bo
Zheng, Yi
Diffenderfer, Kenneth E.
Zhang, Jian
Soltani, Sheila
Eames, Tameji
Schafer, Simon T.
Boyer, Leah
Marchetto, Maria C.
Nurnberger, John I.
Calabrese, Joseph R.
Oedegaard, Ketil J.
McCarthy, Michael J.
Zandi, Peter P.
Alda, Martin
Nievergelt, Caroline M.
Mi, Shuangli
Brennand, Kristen J.
Kelsoe, John R.
Gage, Fred H.
Yao, Jun
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742055
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature15526