RNA therapeutics: beyond RNA interference and antisense oligonucleotides
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
All RNA-targeted therapeutic technologies exploit oligonucleotides that bind to target RNA, but they differ in their mechanism of action and produce different effects.
Small interfering RNAs, antisense oligonucleotides and external guide sequences lead to enzyme-dependent degradation of targeted mRNA. Drugs involving these approach...
Alternative Titles
Full title
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4743652
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4743652
Other Identifiers
ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd3625
