Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer
Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer
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Publisher
Germany: BioMed Central Ltd
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Language
English
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Publisher
Germany: BioMed Central Ltd
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Scope and Contents
Contents
While localized prostate cancer (PCa) can be effectively cured, metastatic disease inevitably progresses to a lethal state called castration-resistant prostate cancer (CRPC). Emerging evidence suggests that aberrant epigenetic repression by the polycomb group (PcG) complexes fuels PCa progression, providing novel therapeutic opportunities.
In th...
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Full title
Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4751702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4751702
Other Identifiers
ISSN
1868-7075,1868-7083
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-016-0182-9