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Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4751702

Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

About this item

Full title

Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2016-02, Vol.8 (1), p.16-16, Article 16

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

While localized prostate cancer (PCa) can be effectively cured, metastatic disease inevitably progresses to a lethal state called castration-resistant prostate cancer (CRPC). Emerging evidence suggests that aberrant epigenetic repression by the polycomb group (PcG) complexes fuels PCa progression, providing novel therapeutic opportunities.
In th...

Alternative Titles

Full title

Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4751702

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4751702

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-016-0182-9

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