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Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers
Author / Creator:Kawakami, Masanori ; Mustachio, Lisa Maria ; Zheng, Lin ; Chen, Yulong ; Rodriguez-Canales, Jaime ; Mino, Barbara ; Kurie, Jonathan M. ; Roszik, Jason ; Villalobos, Pamela Andrea ; Thu, Kelsie L. ; Silvester, Jennifer ; Cescon, David W. ; Wistuba, Ignacio I. ; Mak, Tak W. ; Liu, Xi ; Dmitrovsky, Ethan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.1913-1918
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Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology
Author / Creator:Martinez, Victor D. ; Vucic, Emily A. ; Thu, Kelsie L. ; Hubaux, Roland ; Enfield, Katey S.S. ; Pikor, Larissa A. ; Becker-Santos, Daiana D. ; Brown, Carolyn J. ; Lam, Stephen ; Lam, Wan L.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-05, Vol.5 (1), p.10423, Article 10423
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Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Author / Creator:Safikhani, Zhaleh ; Smirnov, Petr ; Thu, Kelsie L. ; Silvester, Jennifer ; El-Hachem, Nehme ; Quevedo, Rene ; Lupien, Mathieu ; Mak, Tak W. ; Cescon, David ; Haibe-Kains, Benjamin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-10, Vol.8 (1), p.1126-11, Article 1126
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Genomic Deregulation of the E2F/Rb Pathway Leads to Activation of the Oncogene EZH2 in Small Cell Lung Cancer
Author / Creator:Coe, Bradley P. ; Thu, Kelsie L. ; Aviel-Ronen, Sarit ; Vucic, Emily A. ; Gazdar, Adi F. ; Lam, Stephen ; Tsao, Ming-Sound ; Lam, Wan L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-08, Vol.8 (8), p.e71670
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Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer
Author / Creator:Bailey, Swneke D ; Desai, Kinjal ; Kron, Ken J ; Mazrooei, Parisa ; Sinnott-Armstrong, Nicholas A ; Treloar, Aislinn E ; Dowar, Mark ; Thu, Kelsie L ; Cescon, David W ; Silvester, Jennifer ; Yang, S Y Cindy ; Wu, Xue ; Pezo, Rossanna C ; Haibe-Kains, Benjamin ; Mak, Tak W ; Bedard, Philippe L ; Pugh, Trevor J ; Sallari, Richard C ; Lupien, Mathieu
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-10, Vol.48 (10), p.1260-1266
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Alternative Strategies for Delivering Immunotherapeutics Targeting the PD-1/PD-L1 Immune Checkpoint in Cancer
Author / Creator:Hoshi, Ryunosuke ; Gorospe, Kristyna A. ; Labouta, Hagar I. ; Azad, Taha ; Lee, Warren L. ; Thu, Kelsie L.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2024-09, Vol.16 (9), p.1181
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Lung Adenocarcinoma of Never Smokers and Smokers Harbor Differential Regions of Genetic Alteration and Exhibit Different Levels of Genomic Instability
Author / Creator:Thu, Kelsie L. ; Vucic, Emily A. ; Chari, Raj ; Zhang, Wei ; Lockwood, William W. ; English, John C. ; Fu, Rong ; Wang, Pei ; Feng, Ziding ; MacAulay, Calum E. ; Gazdar, Adi F. ; Lam, Stephen ; Lam, Wan L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e33003
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Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development
Author / Creator:Lockwood, William W. ; Wilson, Ian M. ; Coe, Bradley P. ; Chari, Raj ; Pikor, Larissa A. ; Thu, Kelsie L. ; Solis, Luisa M. ; Nunez, Maria I. ; Behrens, Carmen ; Yee, John ; English, John ; Murray, Nevin ; Tsao, Ming-Sound ; Minna, John D. ; Gazdar, Adi F. ; Wistuba, Ignacio I. ; MacAulay, Calum E. ; Lam, Stephen ; Lam, Wan L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-05, Vol.7 (5), p.e37775
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Plug and Pop: A 3D-Printed, Modular Platform for Drug Delivery Using Clinical Ultrasound and Microbubbles
Author / Creator:Joshi, Kushal ; Sanwal, Rajiv ; Thu, Kelsie L. ; Tsai, Scott S. H. ; Lee, Warren L.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-11, Vol.14 (11), p.2516
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Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients
Author / Creator:Sunpaweravong, Patrapim ; Thu, Kelsie L. ; Lam, Wan L. ; Mai, Sabine
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2016-04, Vol.142 (4), p.749-756
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Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer
Author / Creator:Clermont, Pier-Luc ; Crea, Francesco ; Chiang, Yan Ting ; Lin, Dong ; Zhang, Amy ; Wang, James Z. L. ; Parolia, Abhijit ; Wu, Rebecca ; Xue, Hui ; Wang, Yuwei ; Ding, Jiarui ; Thu, Kelsie L. ; Lam, Wan L. ; Shah, Sohrab P. ; Collins, Colin C. ; Wang, Yuzhuo ; Helgason, Cheryl D.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2016-02, Vol.8 (1), p.16, Article 16
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Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology
Author / Creator:Vucic, Emily A ; Thu, Kelsie L ; Pikor, Larissa A ; Enfield, Katey SS ; Yee, John ; English, John C ; MacAulay, Calum E ; Lam, Stephen ; Jurisica, Igor ; Lam, Wan L
Publisher:England: BioMed Central
Journal title:BMC cancer, 2014-10, Vol.14 (1), p.778, Article 778
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Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Author / Creator:Safikhani, Zhaleh ; Smirnov, Petr ; Thu, Kelsie L ; Silvester, Jennifer ; El-Hachem, Nehme ; Quevedo, Rene ; Lupien, Mathieu ; Mak, Tak W ; Cescon, David ; Haibe-Kains, Benjamin
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-01, Vol.9, p.1
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Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma
Author / Creator:Lockwood, William W. ; Chari, Raj ; Coe, Bradley P. ; Thu, Kelsie L. ; Garnis, Cathie ; Malloff, Chad A. ; Campbell, Jennifer ; Williams, Ariane C. ; Hwang, Dorothy ; Zhu, Chang-Qi ; Buys, Timon P. H. ; Yee, John ; English, John C. ; MacAulay, Calum ; Tsao, Ming-Sound ; Gazdar, Adi F. ; Minna, John D. ; Lam, Stephen ; Lam, Wan L.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2010-07, Vol.7 (7), p.e1000315
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Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer
Author / Creator:Lam, Wan L. ; Hubaux, Roland ; Pikor, Larissa A. ; Thu, Kelsie L. ; Vucic, Emily A. ; Martinez, Victor D.
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:BioMed research international, 2014-01, Vol.2014 (2014), p.1-10
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Targeting Kinesins for Therapeutic Exploitation of Chromosomal Instability in Lung Cancer
Author / Creator:Zhang, Christopher ; Wu, Benson Z. ; Thu, Kelsie L.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2025-02, Vol.17 (4), p.685
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AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer
Author / Creator:Kubli, Shawn P. ; Bassi, Christian ; Roux, Cecilia ; Wakeham, Andrew ; Göbl, Christoph ; Zhou, Wenjing ; Jafari, Soode Moghadas ; Snow, Bryan ; Jones, Lisa ; Palomero, Luis ; Thu, Kelsie L. ; Cassetta, Luca ; Soong, Daniel ; Berger, Thorsten ; Ramachandran, Parameswaran ; Baniasadi, Shakiba P. ; Duncan, Gordon ; Lindzen, Moshit ; Yarden, Yosef ; Herranz, Carmen ; Lazaro, Conxi ; Chu, Mandy F. ; Haight, Jillian ; Tinto, Paul ; Silvester, Jennifer ; Cescon, David W. ; Petit, Anna ; Pettersson, Sven ; Pollard, Jeffrey W. ; Mak, Tak W. ; Pujana, Miguel A. ; Cappello, Paola ; Gorrini, Chiara
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (9), p.3604-3613
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CD47: The Next Frontier in Immune Checkpoint Blockade for Non-Small Cell Lung Cancer
Author / Creator:Lau, Asa P. Y. ; Khavkine Binstock, Sharon S. ; Thu, Kelsie L.
Publisher:Basel: MDPI AG
Journal title:Cancers, 2023-11, Vol.15 (21), p.5229
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DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways
Author / Creator:Vucic, Emily A. ; Chari, Raj ; Thu, Kelsie L. ; Wilson, Ian M. ; Cotton, Allison M. ; Kennett, Jennifer Y. ; Zhang, May ; Lonergan, Kim M. ; Steiling, Katrina ; Brown, Carolyn J. ; McWilliams, Annette ; Ohtani, Keishi ; Lenburg, Marc E. ; Sin, Don D. ; Spira, Avrum ; MacAulay, Calum E. ; Lam, Stephen ; Lam, Wan L.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory cell and molecular biology, 2014-05, Vol.50 (5), p.912-922
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E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling
Author / Creator:Dominguez-Brauer, Carmen ; Khatun, Rahima ; Elia, Andrew J. ; Thu, Kelsie L. ; Ramachandran, Parameswaran ; Baniasadi, Shakiba P. ; Hao, Zhenyue ; Jones, Lisa D. ; Haight, Jillian ; Sheng, Yi ; Mak, Tak W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1148-E1157
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Showing 1 to 20 of 34 results

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Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

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Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

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Gene isoforms as expression-based biomarkers predictive of drug response in vitro

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Genomic Deregulation of the E2F/Rb Pathway Leads to Activation of the Oncogene EZH2 in Small Cell Lung Cancer

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Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer

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Alternative Strategies for Delivering Immunotherapeutics Targeting the PD-1/PD-L1 Immune Checkpoint in Cancer

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Lung Adenocarcinoma of Never Smokers and Smokers Harbor Differential Regions of Genetic Alteration and Exhibit Different Levels of Genomic Instability

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Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development

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Plug and Pop: A 3D-Printed, Modular Platform for Drug Delivery Using Clinical Ultrasound and Microbubbles

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Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients

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Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer

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Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology

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Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro

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Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

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Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer

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Targeting Kinesins for Therapeutic Exploitation of Chromosomal Instability in Lung Cancer

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AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer

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CD47: The Next Frontier in Immune Checkpoint Blockade for Non-Small Cell Lung Cancer

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DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways

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E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

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