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Impaired theta-gamma coupling in APP-deficient mice

Impaired theta-gamma coupling in APP-deficient mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4764939

Impaired theta-gamma coupling in APP-deficient mice

About this item

Full title

Impaired theta-gamma coupling in APP-deficient mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-02, Vol.6 (1), p.21948, Article 21948

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Amyloid precursor protein (APP) is critically involved in the pathophysiology of Alzheimer’s disease, but its physiological functions remain elusive. Importantly, APP knockout (APP-KO) mice exhibit cognitive deficits, suggesting that APP plays a role at the neuronal network level. To investigate this possibility, we recorded local field potentials...

Alternative Titles

Full title

Impaired theta-gamma coupling in APP-deficient mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4764939

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4764939

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep21948

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