Quetiapine Ameliorates Schizophrenia-Like Behaviors and Protects Myelin Integrity in Cuprizone Intox...
Quetiapine Ameliorates Schizophrenia-Like Behaviors and Protects Myelin Integrity in Cuprizone Intoxicated Mice: The Involvement of Notch Signaling Pathway
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Author / Creator
Wang, Hua-ning , Liu, Gao-hua , Zhang, Rui-guo , Xue, Fen , Wu, Di , Chen, Yun-chun , Peng, Ye , Peng, Zheng-wu and Tan, Qing-rong
Publisher
US: Oxford University Press
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Language
English
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Publisher
US: Oxford University Press
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Contents
Background:White matter disturbances and myelin impairment are key features of schizophrenia. The antipsychotic drug quetiapine can promote the maturation of oligodendrocytes, but the molecular mechanisms remain largely unknown.Methods:The schizophrenia-like behaviors, degrees of demyelination, and levels of Notch signaling molecules in forebrains...
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Full title
Quetiapine Ameliorates Schizophrenia-Like Behaviors and Protects Myelin Integrity in Cuprizone Intoxicated Mice: The Involvement of Notch Signaling Pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4772821
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4772821
Other Identifiers
ISSN
1461-1457
E-ISSN
1469-5111
DOI
10.1093/ijnp/pyv088
