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Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783171

Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

About this item

Full title

Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2015-11, Vol.350 (6264), p.1089-1092

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The invasion of a suitable host hepatocyte by mosquito-transmitted Plasmodium sporozoites is an essential early step in successful malaria parasite infection. Yet precisely how sporozoites target their host cell and facilitate productive infection remains largely unknown. We found that the hepatocyte EphA2 receptor was critical for establishing a p...

Alternative Titles

Full title

Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783171

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783171

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aad3318

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