Malaria parasites target the hepatocyte receptor EphA2 for successful host infection
Malaria parasites target the hepatocyte receptor EphA2 for successful host infection
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
The invasion of a suitable host hepatocyte by mosquito-transmitted Plasmodium sporozoites is an essential early step in successful malaria parasite infection. Yet precisely how sporozoites target their host cell and facilitate productive infection remains largely unknown. We found that the hepatocyte EphA2 receptor was critical for establishing a p...
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Full title
Malaria parasites target the hepatocyte receptor EphA2 for successful host infection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783171
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aad3318