Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In early mammalian embryos, the genome is transcriptionally quiescent until the zygotic genome activation （ZGA） which occurs 2-3 days after fertilization. Despite a long-standing effort, maternal transcription factors regulating this crucial developmental event remain largely elusive. Here, using maternal and paternal mouse models of Yapl deletion,...
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Full title
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783469
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4783469
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2016.20
