A CCL24-dependent pathway augments eosinophilic airway inflammation in house dust mite-challenged Cd...
A CCL24-dependent pathway augments eosinophilic airway inflammation in house dust mite-challenged Cd163−/− mice
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Author / Creator
Dai, C , Yao, X , Gordon, E M , Barochia, A , Cuento, R A , Kaler, M , Meyer, K S , Keeran, K J , Nugent, G Z , Jeffries, K R , Qu, X , Yu, Z-X , Aponte, A , Gucek, M , Dagur, P K , McCoy, J P and Levine, S J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
CD163 is a macrophage scavenger receptor with anti-inflammatory and pro-inflammatory functions. Here, we report that alveolar macrophages (AMΦs) from asthmatic subjects had reduced cell-surface expression of CD163, which suggested that CD163 might modulate the pathogenesis of asthma. Consistent with this, house dust mite (HDM)-challenged
Cd163
Alternative Titles
Full title
A CCL24-dependent pathway augments eosinophilic airway inflammation in house dust mite-challenged Cd163−/− mice
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4794428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4794428
Other Identifiers
ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2015.94
