Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Biochemical assays using activity-based chemical probes revealed that the Hippo pathway transcription factor TEAD undergoes autopalmitoylation to ensure binding to YAP/TAZ and promote muscle differentiation and tissue growth.
TEA domain (TEAD) transcription factors bind to the coactivators YAP and TAZ and regulate the transcriptional output of t...
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Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4798901
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4798901
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2036
