Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
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London: Nature Publishing
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English
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London: Nature Publishing
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Contents
Calorie restriction extends lifespan in a broad range of organisms, from yeasts to mammals. Numerous hypotheses have been proposed to explain this phenomenon, including decreased oxidative damage and altered energy metabolism. In Saccharomyces cerevisiae, lifespan extension by calorie restriction requires the NAD+-dependent histone deacetylase, Sir...
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Full title
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4802858
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4802858
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature01578
