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Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4811143

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

About this item

Full title

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2016-04, Vol.126 (4), p.1323-1336

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Vascular calcification is a common feature of major cardiovascular diseases. Extracellular vesicles participate in the formation of microcalcifications that are implicated in atherosclerotic plaque rupture; however, the mechanisms that regulate formation of calcifying extracellular vesicles remain obscure. Here, we have demonstrated that sortilin i...

Alternative Titles

Full title

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4811143

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4811143

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI80851

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