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LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4814347

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

About this item

Full title

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2016-04, Vol.18 (4), p.431-442

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cellular processes. However, the potential involvement of lncRNAs in kinase signalling remains largely unknown. AMP-activated protein kinase (AMPK) acts as a critical sensor of cellular energy status. Here we show that the lncRNA
NBR2
(neighbour of
BRCA1
gene...

Alternative Titles

Full title

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4814347

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4814347

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3328

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