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Mutations driving CLL and their evolution in progression and relapse

Mutations driving CLL and their evolution in progression and relapse

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815041

Mutations driving CLL and their evolution in progression and relapse

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Which genetic alterations drive tumorigenesis and how they evolve over the course of disease and therapy are central questions in cancer biology. Here we identify 44 recurrently mutated genes and 11 recurrent somatic copy number variations through whole-exome sequencing of 538 chronic lymphocytic leukaemia (CLL) and matched germline DNA samples, 27...

Alternative Titles

Full title

Mutations driving CLL and their evolution in progression and relapse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815041

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815041

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature15395

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