Mutations driving CLL and their evolution in progression and relapse
Mutations driving CLL and their evolution in progression and relapse
About this item
Full title
Author / Creator
Landau, Dan A. , Tausch, Eugen , Taylor-Weiner, Amaro N. , Stewart, Chip , Reiter, Johannes G. , Bahlo, Jasmin , Kluth, Sandra , Bozic, Ivana , Lawrence, Mike , Böttcher, Sebastian , Carter, Scott L. , Cibulskis, Kristian , Mertens, Daniel , Sougnez, Carrie L. , Rosenberg, Mara , Hess, Julian M. , Edelmann, Jennifer , Kless, Sabrina , Kneba, Michael , Ritgen, Matthias , Fink, Anna , Fischer, Kirsten , Gabriel, Stacey , Lander, Eric S. , Nowak, Martin A. , Döhner, Hartmut , Hallek, Michael , Neuberg, Donna , Getz, Gad , Stilgenbauer, Stephan and Wu, Catherine J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Which genetic alterations drive tumorigenesis and how they evolve over the course of disease and therapy are central questions in cancer biology. Here we identify 44 recurrently mutated genes and 11 recurrent somatic copy number variations through whole-exome sequencing of 538 chronic lymphocytic leukaemia (CLL) and matched germline DNA samples, 27...
Alternative Titles
Full title
Mutations driving CLL and their evolution in progression and relapse
Authors, Artists and Contributors
Author / Creator
Tausch, Eugen
Taylor-Weiner, Amaro N.
Stewart, Chip
Reiter, Johannes G.
Bahlo, Jasmin
Kluth, Sandra
Bozic, Ivana
Lawrence, Mike
Böttcher, Sebastian
Carter, Scott L.
Cibulskis, Kristian
Mertens, Daniel
Sougnez, Carrie L.
Rosenberg, Mara
Hess, Julian M.
Edelmann, Jennifer
Kless, Sabrina
Kneba, Michael
Ritgen, Matthias
Fink, Anna
Fischer, Kirsten
Gabriel, Stacey
Lander, Eric S.
Nowak, Martin A.
Döhner, Hartmut
Hallek, Michael
Neuberg, Donna
Getz, Gad
Stilgenbauer, Stephan
Wu, Catherine J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815041
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature15395