Propagation of conformational changes during μ-opioid receptor activation
Propagation of conformational changes during μ-opioid receptor activation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
NMR spectroscopy reveals the conformational changes of the μ-opioid receptor that are associated with receptor activation, helping to explain why the allosteric coupling between the agonist-binding pocket and the cytoplasmic G-protein-coupling interface of this receptor is relatively weak.
Activation of the μ-opioid receptor
The μ-opioid rece...
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Full title
Propagation of conformational changes during μ-opioid receptor activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4820006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4820006
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14680
