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Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxi...

Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4826841

Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin

About this item

Full title

Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin

Publisher

United States: Elsevier B.V

Journal title

Molecular oncology, 2016-04, Vol.10 (4), p.553-565

Language

English

Formats

Publication information

Publisher

United States: Elsevier B.V

More information

Scope and Contents

Contents

Regulatory T cells (Treg) play an important role in modulating the immune response and has attracted increasing attention in diverse fields such as cancer treatment, transplantation and autoimmune diseases. CC chemokine receptor 4 (CCR4) is expressed on the majority of Tregs, especially on effector Tregs. Recently we have developed a diphtheria-tox...

Alternative Titles

Full title

Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4826841

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4826841

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1016/j.molonc.2015.11.008

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