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High‐Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against...

High‐Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4835244

High‐Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

About this item

Full title

High‐Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

Publisher

Durham, NC, USA: AlphaMed Press

Journal title

Stem cells translational medicine, 2016-05, Vol.5 (5), p.613-627

Language

English

Formats

Publication information

Publisher

Durham, NC, USA: AlphaMed Press

More information

Scope and Contents

Contents

Using astrocytes differentiated from human embryonic stem cells, an assay was developed to identify compounds that protect against oxidative stress, a condition associated with many neurodegenerative diseases. The assay has been optimized for high‐throughput screening in a 1,536‐well plate format. From a screen of approximately 4,100 bioactive tool...

Alternative Titles

Full title

High‐Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4835244

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4835244

Other Identifiers

ISSN

2157-6564

E-ISSN

2157-6580

DOI

10.5966/sctm.2015-0170

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