N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys
N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys
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Author / Creator
Shen, Yang , Miao, Nai-jun , Xu, Jin-lan , Gan, Xin-xin , Xu, Dan , Zhou, Li , Xue, Hong , Zhang, Wei and Lu, Li-min
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aim： To investigate the effects of ROS scavenger N-acetylcysteine （NAC） on angiotensin II （Ang II）-mediated renal fibrosis in vivo and in vitro. Methods： Mice were subjected to unilateral ureteral obstruction （UUO）, and then treated with vehicle or NAC （250 mg/kg, ip） for 7 days. Histological changes of the obstructed kidneys were observed with Mas...
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Full title
N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4857549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4857549
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2016.12
