Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation
Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Transient DNA strand break formation has been identified as an effective means to enhance gene expression in living cells. In the muscle lineage, cell differentiation is contingent upon the induction of caspase-mediated DNA strand breaks, which act to establish the terminal gene expression program. This coordinated DNA nicking is rapidly resolved,...
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Full title
Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860966
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860966
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ISSN
2056-5968
E-ISSN
2056-5968
DOI
10.1038/celldisc.2015.41
