Lead identification for the K-Ras protein: virtual screening and combinatorial fragment-based approa...
Lead identification for the K-Ras protein: virtual screening and combinatorial fragment-based approaches
About this item
Full title
Author / Creator
Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Scope and Contents
Contents
Kirsten rat sarcoma (K-Ras) protein is a member of Ras family belonging to the small guanosine triphosphatases superfamily. The members of this family share a conserved structure and biochemical properties, acting as binary molecular switches. The guanosine triphosphate-bound active K-Ras interacts with a range of effectors, resulting in the stimul...
Alternative Titles
Full title
Lead identification for the K-Ras protein: virtual screening and combinatorial fragment-based approaches
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4861002
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4861002
Other Identifiers
ISSN
1178-6930
E-ISSN
1178-6930
DOI
10.2147/OTT.S99671
