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The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implica...

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4863168

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery

About this item

Full title

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-05, Vol.6 (1), p.25879-25879, Article 25879

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lipofectamine reagents are widely accepted as “gold-standard” for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell imaging, single-particle tracking microscopy and qu...

Alternative Titles

Full title

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4863168

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4863168

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep25879

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