CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and i...
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Inflammation is a common neuropathological feature in several neurological disorders, including amyotrophic lateral sclerosis (ALS). We have studied the contribution of CSF1R signalling to inflammation in ALS, as a pathway previously reported to control the expansion and activation of microglial cells. We found that microglial cell proliferation in...
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Full title
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4865981
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4865981
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep25663
