HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
About this item
Full title
Author / Creator
Jardine, Joseph G. , Kulp, Daniel W. , Havenar-Daughton, Colin , Sarkar, Anita , Briney, Bryan , Sok, Devin , Sesterhenn, Fabian , Ereño-Orbea, June , Kalyuzhniy, Oleksandr , Deresa, Isaiah , Hu, Xiaozhen , Spencer, Skye , Jones, Meaghan , Georgeson, Erik , Adachi, Yumiko , Kubitz, Michael , deCamp, Allan C. , Julien, Jean-Philippe , Wilson, Ian A. , Burton, Dennis R. , Crotty, Shane , Schief, William R. and Scripps Research Inst., La Jolla, CA (United States)
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Induction of broadly neutralizing antibodies (bnAbs) is a major HIV vaccine goal. Germline-targeting immunogens aim to initiate bnAb induction by activating bnAb germline precursor B cells. Critical unmet challenges are to determine whether bnAb precursor naïve B cells bind germline-targeting immunogens and occur at sufficient frequency in humans f...
Alternative Titles
Full title
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
Authors, Artists and Contributors
Author / Creator
Kulp, Daniel W.
Havenar-Daughton, Colin
Sarkar, Anita
Briney, Bryan
Sok, Devin
Sesterhenn, Fabian
Ereño-Orbea, June
Kalyuzhniy, Oleksandr
Deresa, Isaiah
Hu, Xiaozhen
Spencer, Skye
Jones, Meaghan
Georgeson, Erik
Adachi, Yumiko
Kubitz, Michael
deCamp, Allan C.
Julien, Jean-Philippe
Wilson, Ian A.
Burton, Dennis R.
Crotty, Shane
Schief, William R.
Scripps Research Inst., La Jolla, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872700
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872700
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aad9195
