Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
α-Chiral amines are key intermediates for the synthesis of a plethora of chemical compounds at industrial scale. We present a biocatalytic hydrogen-borrowing amination of primary and secondary alcohols that allows for the efficient and environmentally benign production of enantiopure amines. The method relies on a combination of two enzymes: an alc...
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Full title
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4883652
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4883652
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aac9283
