Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Alzheimer's disease (AD) is a progressive, multifactorial neurodegenerative disorder that is the main cause of dementia globally. AD is associated with increased oxidative stress, resulting from imbalance in production and clearance of reactive oxygen species (ROS). ROS can damage DNA and other macromolecules, leading to genome instability and disr...
Alternative Titles
Full title
Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884418
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884418
Other Identifiers
ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-016-0237-z
