A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV...
A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine
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Publisher
United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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Contents
Background. A novel translational pharmacology investigation was conducted by combining an in vitro efficacy target with mucosal tissue pharmacokinetic (PK) data and mathematical modeling to determine the number of doses required for effective human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP). Methods. A PK/pharmacodynamic (PD) mode...
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Full title
A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4907409
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4907409
Other Identifiers
ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiw077
