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TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911334

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

About this item

Full title

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-06, Vol.534 (7607), p.347-351

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

When integral membrane proteins are visualized in detergents or other artificial systems, an important layer of information is lost regarding lipid interactions and their effects on protein structure. This is especially relevant to proteins for which lipids have both structural and regulatory roles. Here we demonstrate the power of combining electr...

Alternative Titles

Full title

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911334

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911334

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature17964

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