Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Metabolic tracer and free energy analysis of metabolic fluxes and pool sizes in
E. coli
, yeast and a mammalian cell line reveals a conservation of absolute metabolite concentrations that is constrained by thermodynamics and efficient enzyme utilization.
In metabolism, available free energy is limited and must be divided across pathway ste...
Alternative Titles
Full title
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4912430
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4912430
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2077
