CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocyto...
CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia
About this item
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Author / Creator
Qiu, Jihua , Liu, Xuena , Li, Xiaoqing , Zhang, Xu , Han, Panpan , Zhou, Hai , Shao, Linlin , Hou, Yu , Min, Yanan , Kong, Zhangyuan , Wang, Yawen , Wei, Yu , Liu, Xinguang , Ni, Heyu , Peng, Jun and Hou, Ming
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In addition to antiplatelet autoantibodies, CD8
+
cytotoxic T lymphocytes (CTLs) play an important role in the increased platelet destruction in immune thrombocytopenia (ITP). Recent studies have highlighted that platelet desialylation leads to platelet clearance via hepatocyte asialoglycoprotein receptors (ASGPRs). Whether CD8
+
T cell...
Alternative Titles
Full title
CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4913243
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4913243
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep27445
