Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography
Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography
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Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Na
+
,K
+
-ATPase transfers three Na
+
from the cytoplasm into the extracellular medium and two K
+
in the opposite direction per ATP hydrolysed. The binding and release of Na
+
and K
+
are all thought to occur sequentially. Here we demonstrate by X-ray crystallography of the ATPase in E2·MgF
4
2−
·2K
Alternative Titles
Full title
Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4918401
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4918401
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9004
