IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection
About this item
Full title
Author / Creator
Younes, Souheil-Antoine , Freeman, Michael L. , Mudd, Joseph C. , Shive, Carey L. , Reynaldi, Arnold , Panigrahi, Soumya , Estes, Jacob D. , Deleage, Claire , Lucero, Carissa , Anderson, Jodi , Schacker, Timothy W. , Davenport, Miles P. , McCune, Joseph M. , Hunt, Peter W. , Lee, Sulggi A. , Serrano-Villar, Sergio , Debernardo, Robert L. , Jacobson, Jeffrey M. , Canaday, David H. , Sekaly, Rafick-Pierre , Rodriguez, Benigno , Sieg, Scott F. and Lederman, Michael M.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
In HIV-1-infected patients, increased numbers of circulating CD8+ T cells are linked to increased risk of morbidity and mortality. Here, we identified a bystander mechanism that promotes CD8 T cell activation and expansion in untreated HIV-1-infected patients. Compared with healthy controls, untreated HIV-1-infected patients have an increased popul...
Alternative Titles
Full title
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection
Authors, Artists and Contributors
Author / Creator
Freeman, Michael L.
Mudd, Joseph C.
Shive, Carey L.
Reynaldi, Arnold
Panigrahi, Soumya
Estes, Jacob D.
Deleage, Claire
Lucero, Carissa
Anderson, Jodi
Schacker, Timothy W.
Davenport, Miles P.
McCune, Joseph M.
Hunt, Peter W.
Lee, Sulggi A.
Serrano-Villar, Sergio
Debernardo, Robert L.
Jacobson, Jeffrey M.
Canaday, David H.
Sekaly, Rafick-Pierre
Rodriguez, Benigno
Sieg, Scott F.
Lederman, Michael M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4922693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4922693
Other Identifiers
ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI85996
