Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support forma...
Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes
About this item
Full title
Author / Creator
MacDonald, Douglas A. , Martin, Joel , Muthusamy, Kathir K. , Luo, Jiann-Kae , Pyles, Erica , Rafique, Ashique , Huang, Tammy , Potocky, Terra , Liu, Yang , Cao, Jingtai , Bono, Françoise , Delesque, Nathalie , Savi, Pierre , Francis, John , Amirkhosravi, Ali , Meyer, Todd , Romano, Carmelo , Glinka, Meredith , Yancopoulos, George D. , Stahl, Neil , Wiegand, Stanley J. and Papadopoulos, Nicholas
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
Formats
Publication information
Publisher
Dordrecht: Springer Netherlands
Subjects
More information
Scope and Contents
Contents
Anti-vascular endothelial growth factor (VEGF) therapies have improved clinical outcomes for patients with cancers and retinal vascular diseases. Three anti-VEGF agents, pegaptanib, ranibizumab, and aflibercept, are approved for ophthalmic indications, while bevacizumab is approved to treat colorectal, lung, and renal cancers, but is also used off-...
Alternative Titles
Full title
Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes
Authors, Artists and Contributors
Author / Creator
Martin, Joel
Muthusamy, Kathir K.
Luo, Jiann-Kae
Pyles, Erica
Rafique, Ashique
Huang, Tammy
Potocky, Terra
Liu, Yang
Cao, Jingtai
Bono, Françoise
Delesque, Nathalie
Savi, Pierre
Francis, John
Amirkhosravi, Ali
Meyer, Todd
Romano, Carmelo
Glinka, Meredith
Yancopoulos, George D.
Stahl, Neil
Wiegand, Stanley J.
Papadopoulos, Nicholas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4930479
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4930479
Other Identifiers
ISSN
0969-6970
E-ISSN
1573-7209
DOI
10.1007/s10456-016-9515-8