Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Gad Getz and colleagues analyze mutational patterns in urothelial cancer and find a strong association between mutations in the nucleotide excision repair gene
ERCC2
and a distinct mutational signature. They also find that the activity of this signature is associated with smoking, independently of
ERCC2
mutational status.
Alterations...
Alternative Titles
Full title
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936490
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936490
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.3557
