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FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4940300

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

About this item

Full title

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2016-08, Vol.35 (33), p.4335-4344

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2 and AR crosstalk and regulate hormone-dependent gene exp...

Alternative Titles

Full title

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4940300

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4940300

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2015.496

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