CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injur...
CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism
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England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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IntroductionCD248 (endosialin) is a stromal cell marker expressed on fibroblasts and pericytes. During liver injury, myofibroblasts are the main source of fibrotic matrix.ObjectiveTo determine the role of CD248 in the development of liver fibrosis in the rodent and human setting.DesignCD248 expression was studied by immunostaining and quantitative...
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CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941145
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941145
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ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2014-308325