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CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injur...

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injur...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941145

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

About this item

Full title

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

Publisher

England: BMJ Publishing Group LTD

Journal title

Gut, 2016-07, Vol.65 (7), p.1175-1185

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

IntroductionCD248 (endosialin) is a stromal cell marker expressed on fibroblasts and pericytes. During liver injury, myofibroblasts are the main source of fibrotic matrix.ObjectiveTo determine the role of CD248 in the development of liver fibrosis in the rodent and human setting.DesignCD248 expression was studied by immunostaining and quantitative...

Alternative Titles

Full title

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941145

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941145

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2014-308325

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