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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941147

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

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England: BMJ Publishing Group

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ObjectivePeroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we investigated the effect of hepatocyte PPARα on non-alcoholic fatty liver disease (NAFLD).DesignWe constructed a novel hepatocyte-specific PPARα knockout (Ppar...

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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941147

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941147

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ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2015-310798

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