The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by b...
The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation
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England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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BackgroundGroup 2 innate lymphoid cells (ILC2) are an important source of the type 2 cytokines interleukin (IL)-5 and IL-13 that are critical to the allergic airway phenotype. Previous studies reported that histone deacetylase (HDAC) inhibition by trichostatin A (TSA) downregulated adaptive allergic immune responses; however, the effect of HDAC inh...
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The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941189
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4941189
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ISSN
0040-6376
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2015-207728
