Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell pro...
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors
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Athens: D.A. Spandidos
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English
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Athens: D.A. Spandidos
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Contents
We identified phosphatidylinositol glycan anchor biosynthesis, class X (PIGX), which plays a critical role in the biosynthetic pathway of glycosylphosphatidylinositol (GPI)-anchor motif, to be upregulated highly and frequently in breast cancer cells. Knockdown of PIGX as well as reticulocalbin 1 (RCN1) and reticulocalbin 2 (RCN2), which we found to...
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Full title
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4948962
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4948962
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ISSN
1019-6439
E-ISSN
1791-2423
DOI
10.3892/ijo.2016.3607