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Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961202

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

About this item

Full title

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8290-8295

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Prostate cancer (CaP) is the most common adult male cancer in the developed world. The paucity of biomarkers to predict prostate tumor biology makes it important to identify key pathways that confer poor prognosis and guide potential targeted therapy. Using a murine forward mutagenesis screen in a Pten-null background, we identified peroxisome prol...

Alternative Titles

Full title

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961202

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961202

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1601571113

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