The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors
The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors
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Author / Creator
Lu, JingWei , Plank, Terra-Dawn , Su, Fang , Shi, XiuJuan , Liu, Chen , Ji, Yuan , Li, ShuaiJun , Huynh, Andrew , Shi, Chao , Zhu, Bo , Yang, Guang , Wu, YanMing , Wilkinson, Miles F and Lu, YanJun
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Inflammatory myofibroblastic tumors (IMTs) are characterized by myofibroblast proliferation and an inflammatory cell infiltrate. Little is known about the molecular pathways that precipitate IMT formation. Here, we report the identification of somatic mutations in UPF1, a gene that encodes an essential component of the nonsense-mediated RNA decay (...
Alternative Titles
Full title
The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966300
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI86508
