Danazol Treatment for Telomere Diseases
Danazol Treatment for Telomere Diseases
About this item
Full title
Author / Creator
Townsley, Danielle M , Dumitriu, Bogdan , Liu, Delong , Biancotto, Angélique , Weinstein, Barbara , Chen, Christina , Hardy, Nathan , Mihalek, Andrew D , Lingala, Shilpa , Kim, Yun Ju , Yao, Jianhua , Jones, Elizabeth , Gochuico, Bernadette R , Heller, Theo , Wu, Colin O , Calado, Rodrigo T , Scheinberg, Phillip and Young, Neal S
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a study designed to assess whether danazol could slow the rate of telomere attrition in a group of patients with short telomeres, 11 of 12 patients actually had telomere elongation over 24 months of therapy.
Telomeres are repeated hexanucleotides and associated proteins that are located at the ends of linear chromosomes; telomeres function to...
Alternative Titles
Full title
Danazol Treatment for Telomere Diseases
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4968696
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4968696
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1515319
