microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disea...
microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disease triple transgenic mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The abnormal regulation of amyloid-β (Aβ) metabolism (e.g., production, cleavage, clearance) plays a central role in Alzheimer’s disease (AD). Among endogenous factors believed to participate in AD progression are the small regulatory non-coding microRNAs (miRs). In particular, the miR-132/212 cluster is severely reduced in the AD brain. In previou...
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microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer’s disease triple transgenic mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4971468
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4971468
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30953
